产品货号：
Z23319
中文名称：
PCSK4抗体
英文名称：
Anti-PCSK4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PCSK4 Antibody |
| 指标别名 | proprotein convertase subtilisin/kexin type 4;PC4;SPC5;PCSK4 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB |
| 基因名称 | PCSK4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of mouse Proprotein convertase PC4(117-133aa DPWFSKQWYMNKEIQQD),different from the related rat sequence by one amino acid. |
| 实际分子量 | 83KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PCSK4(Proprotein Convertase,Subtilisin/Kexin-Type,4),is an enzyme that in humans is encoded by the PCSK4 gene.The gene for PC4(Pcsk4 locus) was mapped to mouse chromosome 10,close to the adipsin locus and near the gene encoding anti-mullerian hormone.Qiu et al.(2005) found that aberrant processing of pro-IGF2 by PC4 may be a cause of IUGR.PC4 cleaved pro-IGF2 to generate the intermediate processed form,IGF2(1-102).Mature IGF2(1-67),likely resulting from further processing by carboxypeptidases,is capable of activating invasive trophoblast cells through AKT phosphorylation.Inhibition of PC4 by a PC4-specific inhibitor blocked pro-IGF2 processing and reduced trophoblast cell migration. |
| Uniprot ID | P29121 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | proprotein convertase subtilisin/kexin type 4 |
| 蛋白名全称 | Proprotein convertase subtilisin/kexin type 4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：PCSK4抗体，PCSK4多抗，Anti-PCSK4 Antibody